A combination injectable antibiotic containing Cefoperazone Sodium 1000 mg and Sulbactam Sodium 500 mg for clinician-directed treatment of susceptible bacterial infections.
Cefoperazone targets susceptible bacteria, while sulbactam inhibits beta-lactamase enzymes that can otherwise undermine antibiotic activity.
Cefoperazone is a broad-spectrum cephalosporin antibiotic. It acts by inhibiting bacterial cell-wall synthesis and is used against a range of Gram-negative bacteria, including Pseudomonas aeruginosa, E. coli, and Klebsiella, as well as Gram-positive bacteria. It rapidly reaches therapeutic levels in systemic tissues, bile, and body fluids.
Sulbactam inhibits beta-lactamase enzymes produced by resistant bacteria, helping restore cefoperazone activity and broaden antimicrobial coverage. It also has intrinsic antimicrobial activity against certain pathogens, including Acinetobacter species.
May be prescribed for severe hospital-acquired pneumonia, bronchitis, and lung abscesses caused by susceptible bacteria.
May be used in the management of peritonitis, cholecystitis, and cholangitis when clinically appropriate.
Applications include complicated pyelonephritis, recurrent urinary tract infections, pelvic inflammatory disease, and endometritis caused by susceptible organisms.
May be prescribed for bloodstream infections and post-surgical wound infections as determined by a qualified healthcare professional.
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